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About AID Knowledge

About AID Knowledge

Appraising and Including Different Knowledge in Guideline Development

Evidence-based guidelines whether national, regional or developed by specialty groups, must search for, and explicitly consider, evidence from sources other than conventional clinical trials and their quantitative data. This need for appraising and including knowledge from a wide variety of sources in guideline development is well recognised. However, how to properly appraise (judge) and include (integrate) different kinds of knowledge remains unclear.

Cited from Wieringa S, Dreesens D, Forland F on behalf of the AID Knowledge Working Group of the Guidelines International Network, et al Different knowledge, different styles of reasoning: a challenge for guideline development BMJ Evidence-Based Medicine 2018;23:87-91.

Working Group Aim

To bring guideline developers together, in order to

  • Identify methods and promising initiatives for appraising and including a wider range of knowledge sources in guidelines;
  • Share experiences with such methods and their application in practice;
  • Identify areas / questions for which methods are wanting
  • Develop methods for appraising and integrating different knowledge

We also aim to support capacity building and to foster collaboration among guideline developers worldwide in this area of methodological uncertainty.

Additional Information

  • Founding position paper in the BMJ: see here.
  • Most recent AID Knowledge paper on Different knowledge, different styles of reasoning in BMJ Evidence-Based Medicine: see here.

How to Join?

GIN members who are interested in joining the WG or any of the sub-groups, should write to: indicating the topic they are most interested in, and they will be added to the respective email list.

Affiliations to Related Initiatives

AID Knowledge has liaised with several other groups to ensure maximised learning and minimised duplication of efforts.

Those groups include:

  • Cochrane Effective Practice and Organisation of Care Group, (EPOC)
  • Cochrane Qualitative Methods Group
  • Evaluation of Genomic Applications in Practice and Prevention (EGAPP)
  • GIN Allied Health Group
  • GRADE Working Group
  • Project on a Framework for Rating Evidence in Public Health (PRECEPT)

If you are aware of / involved in an initiative that we should become aware of, please contact

Page last updated: Jan 19, 2021
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