Nicola Magrini, a medical doctor with a specialty in Clinical Pharmacology, has 20 years experience in drug evaluation, evidence synthesis, guideline development and pharmaceutical policies. He started his career in academia at the University of Bologna and Mario Negri Institute working on clinical trials, metanalysis, and pharmacoepidemiology. A founder member of the Italian Cochrane Centre in 1994 and established a NHS Centre on knowledge brokering and guideline development (NHS CeVEAS, Centre for the evaluation of the effectiveness of Health care) in Modena, Italy from 1999 till 2012. Director of the WHO Collaborating Centre for Evidence-Based Research Synthesis and Guideline Development from 2008 until 2014. He has a special interest in research ethics and active participation in clinical trials. He was scientist at WHO Geneva as Secretary of the Expert Committee on the Selection and Use of Essential Medicines from 2014 to 2020. He is currently (from March 2020) Director General of AIFA, the Italian Medicines Agency.