This section provides links to high quality, recent resources to guide users  to a range of information for those interested in the planning, development, implementation, updating and evaluation of clinical practice guidelines, especially from an international perspective. In addition, it includes:

  • our curated collection of evidence and guidance resources for Covid-19
  • papers and presentations from the GIN Board,  GIN Trustees and our working groups

GIN Publications

Publications by the GIN Board of Trustees and GIN Working Groups

From time to time, the Board receives questions from members to provide guidance in difficult or contentious areas. Where a need for specific guidance is established, the Board, or a subset of Trustees will collaborate to write a paper on the topic to address the issue. Members of our working groups also collaborate to write and publish papers. These papers can be found below.

October 2020

Sanabria AJ, Pardo-Hernandez P,  Ballesteros M, Canelo-Aybar C, McFarlane E, Niño de Guzman E, Penman K, Posso M, Roqué i Figuls M, Selva A, Vernooij RMW, Alonso-Coello P on behalf of GIN Updating Guidelines Working Group and Collaborators. The UpPriority tool was developed to guide the prioritization of clinical guideline questions for updating. Journal of Clinical Epidemiology, 126, 2020, 80-92,

September 2020

Munn Z, Twaddle S, Service D, Harrow E, Okwen PM, Schünemann H, Vandvik PO. Developing Guidelines Before, During, and After the COVID-19 Pandemic. Ann Intern Med. 2020 Sep 15:M20-4907. 

June 2020

Munn Z,  Brandt L,  Kuijpers T; Whittington C, Wiles L, Karge T, on behalf of the G-I-N Tech Working Group. Are systematic review and guideline development tools useful? A Guidelines International Network survey of user preferences. Int J Evid Based Healthc. 2020 Jun 1.

April 2018

Wieringa S, Dreesens D, Forland F, Hulshof C, Lukersmith S, Macbeth F, Shaw B,  van Vliet AK, Zuiderent-Jerak T on behalf of the AID Knowledge Working Group.   Different knowledge, different styles of reasoning: a challenge for guideline development.  BMJ Evid Based Med. 2018 Jun;23(3):87-91

May 2017

Doust J, Vandvik PO, Qaseem A, Mustafa RA, Horvath AR, Frances A, Al-Ansary L, Bossuyt P, Ward RL, Kopp I, Gollogly L, Schunemann H, Glasziou P; Guidelines International Network (G-I-N) Preventing Overdiagnosis Working Group.   Guidance for Modifying the Definition of Diseases; A Checklist .  JAMA Intern Med. 2017 Jul 1;177(7):1020-1025.

January 2016

Nothacker M, Stokes T, Shaw B, Lindsay P, Sipilä R, Follmann M, Kopp I; Guidelines International Network (G-I-N) Performance Measures Working Group. Reporting standards for guideline-based performance measures. Implementation Science 2016, 11:6.

October 2015

Schünemann HJ, Al-Ansary LA, Forland F, Kersten S, Komulainen J, Kopp IB, Macbeth F, Phillips SM, Robbins C, van der Wees P, Qaseem A; Board of Trustees of the Guidelines International Network. G-I-N: Principles for Disclosure of Interests and Management of Conflicts in Guidelines. Ann Intern Med. 2015 Oct 6;163(7):548-53.

April 2012

Qaseem A, Forland F, Macbeth F, Ollenschläger G, Phillips S, van der Wees P; Board of Trustees of the Guidelines International Network.  Guidelines International Network: toward international standards for clinical practice guidelines.   Ann Intern Med. 2012 Apr 3;156(7):525-31.

February 2012

Van der Wees P, Qaseem A, Kaila M,  Ollenschlaeger G, Rosenfeld R, Board of Trustees of the Guidelines International Network (G-I-N).  Prospective systematic review registration: perspective from the Guidelines International Network (G-I-N). Syst Rev. 2012 Feb 9;1:3.

INGUIDE training

INGUIDE is a comprehensive, evidence-based and up-to-date training program for anyone involved in the guideline development process. It is the product of a partnership between leaders in the field of guideline development – Guidelines International Network (GIN) , a global network of guideline producing organisations and guideline participants, and world-renowned experts in guideline research, development and implementation at McMaster University’s Department of Health Research Methods, Evidence, and Impact.

There are four progressive levels of training, from beginner to instructor.  The Level 1 course was first launched in 2020 and was adapted to be fully online.

Registration fees for all levels are discounted for GIN members.  To find out more and to enrol, visit the INGUIDE website.

GIN Webinars

Here you will find a series of GIN webinars, some have been presented centrally, others by our Working Groups, Regional Communities or partners.

To see all of our recordings and keep up to date with our webinars, subscribe to our YouTube channel.

In September 2020, GIN presented a series of four webinars over three days, in place of the 2020 conference, which was postponed due to the pandemic.  This series was named “GIN 2020 – Pit-stop in the Covid-19 marathon for the guideline community”

The webinars were entitled:

  1. Quality of Evidence for guidelines and recommendations
  2. Rapid Guideline Development
  3. Recommendation Mapping
  4. Living Recommendations

View all COVID Pitstop recordings on our YouTube channel.

 Covid-19 webinars

A series of webinars were presented during the period May to August 2020 in response to the global pandemic.

  • Global guidance and local application during the COVID-19 pandemic: best practice for adaptation of guidelines, Aug 19, 2020. You can view the webinar on  YouTube
  • Living Evidence & Guidance for COVID-19; opportunities and challenges for developers, publishers and end-users,  Jul 21, 2020. You can view the webinar on  YouTube
  • AID Knowledge Webinar: COVID-19 – Which crisis? Whose evidence? Robust and inclusive evidence for rapid outbreak guidance, Jun 05, 2020. You can view the webinar on YouTube
  • COVID-19 Pandemic: Navigating Evidence and Guidance in a Crisis May 20, 2020. You can view the webinar on our YouTube Channel.

Working Group & Regional Community Webinars


Nov 27, 2020 First nations-led guideline development – supporting prevention and management of Covid-19 in primary healthcare.  A recording of the webinar can be found here.


Jun 29, 2020 Shared learnings and practical guidance on how to cultivate effective collaboration between guideline developers and HTA producers. A recording can be found here.


March 2021 – GIN NA & The NY Academy of Medicine -Section on Evidence Based Healthcare – Present E-GAPPS IV: COVID-19 & the Challenge to Guidance: Virtual Conference & Open Space Meeting. View the recording here.

December 2, 2020 North American Bringing Evidence & Guidelines Into the Digital Age Recording of the webinar can viewed here

October 30, 2020 North American Systematic Review Methods Virtual Research Day “North American Systematic Review Methods”

Dec 19, 2019  “GRADE – Exploring the Synergy Between Health Technology Assessment (HTA) and Guideline Communities “

Apr 25, 2019 “GRADE – What’s New, What’s Next”

Apr 11, 2019  “A New Online Approach to Engaging Patients and Caregivers in Guideline Development”

Nov 29, 2018 “The Evidence-to-decision Framework” 

Aug 27, 2018 “Using Modeling for Guideline Development”

Apr 23, 2018 “PRELIMINARY RESEARCH FINDINGS:   “What factors influence guideline panel decision making?”

Mar 27, 2018 “The Philosophy and Approach to Public Comment”

Feb 27, 2018 “Task Exchange: Find A Project Helper”

 Dec 19, 2017 The AGREE Ecosystem – Tools To Support Guideline Development, Reporting And Evaluation”

Nov 08, 2017 Multiple Chronic Conditions: The Balance of Benefits and Harms

Jun 29, 2017 “Guideline Development for Non‐Physician Clinicians” 

May 30, 2017 “U.S. Preventive Services Task Force (USPSTF) Methods For Making Recommendations For Diverse Populations”

Dec 12, 2016 What is the ‘Secret Sauce’ in Engaging Stakeholders?’

Aug 09, 2016 Guidelines, Implementation Science, and Where Do We Go From Here?

Jun 21, 2016 A Preview of the National Guidelines Clearinghouse and the National Quality Measures Clearinghouse Websites

Mar 29, 2016 Choosing Wisely® and the Role for Guidelines

Jan 12, 2016 Guidelines International Network: Benefits and Opportunities

Nov 17, 2015 Assessing the Impact of Social Media on Dissemination and Implementation of Clinical Practice Guidelines

Sep 30, 2015.Introduction to the Documentation and Appraisal Review Tool (DART) for evaluating the quality of systematic reviews


  • May 11, 2016 New Developments In GRADE. A recording of the webinar can be viewed here.
  • Apr 13, 2016 GRADE Evidence to Decision Frameworks: Experience and use for Guideline Adaptation and Adoption. A recording can be viewed here.

Guideline Tools

This section contains links to tools of relevance to those developing, adapting, updating, implementing and appraising clinical guidelines which are free to use. If you wish to suggest additional tools to be included, please contact Allison Smith.

1. Checklists for Guidelines

GIN/McMaster Guideline Checklist

The Guideline Development Checklist project is a partnership between the Guidelines International Network (GIN) and McMaster University. The checklist is designed to serve as an interactive resource, with links to learning tools and training materials, for those interested in beginning, enhancing or evaluating their guideline development process. Its use will support the development and implementation of trustworthy guidelines. 

The checklist is also available in Chinese, Italian, Japanese, Polish, Spanish and Thai versions.

The online and pdf versions of the checklist, as well as a glossary of terms and tutorials, are available on the checklist website here

CheckUp: Checklist for the Reporting of Updated Guidelines

The Checklist for the Reporting of Updated Guidelines (CheckUp)  is the result of a partnership of the Iberoamerican Cochrane Centre (, the AGREE Collaboration (, and the GIN Updating Guidelines Working Group (LINK WEB PAGE). CheckUp can be used to evaluate the completeness of reporting in updated guidelines and as a tool to inform guideline developers about reporting requirements.  Adherence to CheckUp will enhance the comprehensiveness and transparency of clinical guideline updating for the benefit of patients and the public, health care professionals, and other relevant stakeholders.  CheckUp is available here

The UpPriority Tool

The UpPriority tool was developed by the GIN Updating Guidelines Working Group and Collaborators. The tool aims to standardise the prioritisation processes when updating clinical guidelines, through consideration of six items. UpPriority is available here.

2. Guideline appraisal tools

The AGREE Instrument

The Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument evaluates the process of practice guideline development and the quality of reporting. AGREE II, launched in 2010, is the international tool for the assessment of practice guidelines and comprises of 23 items organised into the original 6 quality domains. AGREE II is available in 20 languages.

More information on AGREE, the instrument and translations are available here

GLIA (Guideline Implementability Appraisal)

The objective of GLIA is to provide a tool for the appraisal of the implementability of clinical guidelines. Implementability refers to a set of guideline characteristics that predict potential challenges to effective implementation. In addition to a series of questions that inquire about global aspects of a guideline’s implementability, the instrument explores 8 dimensions of individual recommendations. The tool was updated in 2011 and is available here

3. Adaptation tools

The ADAPTE Manual and Resource Toolkit for guideline adaptation

The ADAPTE Collaboration has developed a systematic approach for the adaptation of guidelines produced for the use in one cultural and organisational context to be used in a different cultural and organisational context. The ADAPTE Toolkit is freely available for use, however, charges may be levied by some organisations for use of their guideline, which may be subject to copyright.  The ADAPTE Resource Toolkit for Guideline Adaptation is available below in English and Portugese.

4. Guideline Implementation

GIN Presentations

This section contains key presentations given by GIN Trustees about the work of GIN

  • Meeting: International Scientific and Practice Conference. ‘ Health technology assessment: perspectives of integration in the Commonwealth of Independent States’  2019
    Presentation title: Trustworthy guidelines in the Evidence Ecosystem, for Russia moving forward?         
    Presented by: Per Vandvik, GIN Trustee
    Trustworthy guidelines in the Evidence Ecosystem
  • Meeting: SAGE Summit 2016 
    Presentation title: The Clinical Guidance Landscape in Africa: Introducing the African G-I-N Community 
    Presented by: Okwen Patrick Mbah, GIN Trustee
    The Clinical Guidance Landscape in Africa

Covid-19 Evidence Resources

Our aim is to provide the most comprehensive overview of available resources for our members and to avoid duplicating efforts, especially as evidence in this area is constantly under review and being updated.  It is for members and guests to select the most relevant resources for their setting.

If your organisation has any relevant resources, especially in languages other than English, please email the links and a short description to

Evidence Resources

Rapid Reviews

Evidence maps

Recommendation Maps

Databases of studies



  • Archive of unpublished manuscripts: Medrxiv

Registries of studies in progress

Ongoing studies

WHO Solidarity trial

 Other evidence resources

General Information on COVID-19


Covid-19 Guidance Resources

Our aim is to provide the most comprehensive overview of available resources for our members and to avoid duplicating efforts, especially as guidance in this area is constantly under review and being updated.  It is for members and guests to select the most relevant resources for their setting.

If your organisation has any relevant resources, especially in languages other than English, please email the links and a short description to

GIN Member Zone

Guideline Development and Adaptation

Free Resources 


GIN Collaborations


Resources from members

Relevant Guideline publications

Dagens A et al.Scope, quality, and inclusivity of clinical guidelines produced early in the covid-19 pandemic: rapid review.


All materials presented in this section are from GIN member organisations or other trusted sources. No quality assessments have been undertaken by GIN.

 Repositories of guidelines

  Living Guidelines

 Registries of guidelines in development 

Guidance from GIN Members

  Guidance from other organisations

To network and actively collaborate with the guideline community, become a GIN member today!